In chemical industries, precision and efficiency matter immensely, especially in processes requiring liquid-liquid separation. A mixer settler is a vital apparatus that enables high-purity and scalable extraction by harnessing solubility differences between immiscible liquids. This equipment ensures effective phase mixing and settling, making it indispensable for operations ranging from rare earth extraction to nuclear fuel processing. Its customized configurations and reliable performance address the stringent needs of various sectors, including pharmaceuticals, nutraceuticals, cosmetics, and industrial chemical production. Understanding the capabilities and advantages of mixer settlers clarifies why they hold an essential place in modern chemical manufacturing.

Understanding Mixer Settlers
What is a Mixer Settler?
A mixer settler is a specialized piece of equipment designed for the liquid-liquid extraction process. This process separates two immiscible phases based on the selective solubility of chemical components, which is crucial in purifying complex mixtures. The device typically combines a mixing section and a settling section into one unit, enabling rapid blending and controlled phase separation within the same apparatus. Materials like polypropylene (PP), polyvinyl chloride (PVC), and stainless steel (SUS) are often used, chosen for corrosion resistance and durability. Plate thickness may vary between 5mm to 10mm depending on pressure and chemical resistance requirements. Various production methods - including welding, bonding, bending, injection molding, and integral forming - are utilized to meet diverse industrial needs.
Mixer settlers come in various configurations such as desktop base editions, mobile standard editions, and environmentally friendly high editions, each matching specific operational scales and environmental considerations. Mixing volumes range from small laboratory sizes like 200ml to large industrial capacities up to 3L or customized solutions, addressing research through mass production demands. Equipped with optional features such as temperature control devices, pH adjustment systems, and anti-overflow tanks, these units offer extensive flexibility for precise process control in chemical separation.
How Does a Mixer Settler Work?
The operational principle of mixer settlers involves two main stages: mixing followed by settling. Initially, the agitator blends two immiscible liquids - commonly aqueous and organic phases - carefully optimizing interaction time and intensity to promote mass transfer. The effective agitation facilitates the partitioning of target compounds based on solubility differences. After the mixing stage, the fluid mixture moves into the settling compartment, where gravity assists in phase separation. Adjustable weirs and phase interface height controls allow operators to fine-tune the separation interface to achieve maximum purity.
Modern mixer settlers incorporate advanced features such as patented baffle designs to prevent bubbling and ensure stable phase stratification. Sensor integration monitors variables like pH, temperature, and liquid levels for automated process management via programmable logic controllers (PLCs). This continuous modular setup supports multi-step extraction within a compact footprint, enhancing throughput while conserving floor space.

Comparing Mixer Settlers with Other Separation Technologies
Mixer Settler vs Extraction Column
When evaluating mixer settlers against extraction columns, operational flexibility and ease of maintenance surface as key differentiators. Extraction columns, such as packed or pulsed columns, provide excellent contact area over large volumes enabling high separation efficiency in continuous processes. However, they often require substantial footprint and complex internals, resulting in higher maintenance demands.
Mixer settlers excel in handling wide viscosity ranges and slurries with solids, offering greater adaptability for batch or semi-continuous operations. They allow for precise control over agitator speed and settling parameters and demonstrate robustness in corrosive environments. Case studies show that for batch extractions in pharmaceutical applications where customizable parameters are vital, mixer settlers deliver superior results with reduced solvent consumption and downtime.
Mixer Settler vs Centrifuge
Centrifuges leverage centrifugal force for quick and effective phase separation, especially in high-throughput industrial settings. They are well-suited for fine suspensions and small droplet dispersions but entail higher operational costs and energy usage. Additionally, centrifugation equipment requires stringent maintenance to prevent wear and unbalance issues.
Conversely, mixer settlers operate with lower energy consumption and provide gentle separation conditions ideal for sensitive compounds such as botanical extracts and natural ingredients in cosmetics production. This low shear environment preserves bioactive components avoiding degradation. These features make mixer settlers more appropriate for processes prioritizing product integrity and regulatory compliance, balancing performance with cost-effectiveness.

Advantages and Applications of Mixer Settlers
Advantages of Mixer Settlers
Here are the core advantages of this device that make it a preferred choice across chemical industries:
- High extraction rate and optimal separation efficiency are achieved through precise adjustment of agitator speed, stage quantity, and phase interface height. This level of control enhances product purity and yield.
- The zero-leakage design, enabled by seamless welding and PTFE seals, virtually eliminates contamination risks while ensuring operator safety in handling hazardous media.
- Sturdy construction with corrosion-resistant materials like SUS316L and PTFE broadens applicability across acidic and alkaline media over a pH range of 1-14, ensuring longevity.
- Modular configurations support easy expansion or customization aligned with evolving production requirements, significantly reducing downtime during process adaptations.
- Optional functions such as temperature and pH control devices offer fine-tuning capabilities for complex separation chemistries, preserving delicate compounds in personal care and food-grade applications.
These advantages can effectively solve many production challenges common in pharmaceutical R&D, nutraceutical scale-up, and industrial chemical manufacture, enabling companies to maintain competitive edges through improved process reliability.
Mixer Settler Applications
The versatility of mixer settlers spans several industries and specialized processes:
- Rare Earth Extraction: Efficient purification of critical elements such as neodymium and dysprosium, integral to electronics and renewable technologies, is achieved through solvent extraction stages optimized within mixer settlers.
- Battery Recycling: Recovery of lithium and cobalt from spent electric vehicle batteries reduces environmental impact and addresses supply chain sustainability, facilitated by high-precision extraction setups.
- Nuclear Industry: Safe and selective separation of uranium and plutonium ensures fuel reprocessing and supports non-proliferation controls through chemically robust separation channels.
- Wastewater Treatment: Removal of hazardous heavy metals like copper and zinc protects ecosystems by enabling efficient precipitation and ion-exchange processes within controlled solvent environments.
These applications demonstrate the capability of mixer settlers to adapt to diverse chemistries and regulatory demands while supporting environmentally sustainable practices.

Optimizing Mixer Settler Performance
Efficiency Improvement Techniques
Enhancing the performance of mixer settlers involves several strategies. Accurate calibration of agitator speed impacts phase dispersion and mass transfer rates, directly influencing extraction yield. Employing temperature control devices stabilizes reaction kinetics and solvent properties, ensuring consistent extraction outcomes. Adjusting the stage count allows multi-step separations within a compact assembly. Integration of sensors for real-time pH and liquid level monitoring facilitates dynamic process adjustments, reducing waste and improving process safety.
Additionally, using corrosion-resistant materials and precision manufacturing techniques such as CNC machining and robotic welding extends equipment life and maintains performance under demanding chemical exposures. Optimization reduces power consumption by 15-20% compared to traditional models, aligning with energy efficiency goals.
Troubleshooting and Maintenance Tips
Routine maintenance ensures uninterrupted operation. Key practices include regular inspection of seals and weld joints to prevent leaks, cleaning with deionized water after each batch to avoid contamination build-up, and replacing wear parts like agitator blades annually. Addressing common issues such as phase emulsification or interface instability can often be resolved by fine-tuning agitator speed or adjusting weir heights.
Implementing scheduled preventive maintenance minimizes downtime and maximizes equipment longevity, crucial in facilities where process operability directly impacts production lines and regulatory compliance.

Purchasing and Supplier Information
Buying Mixer Settlers
Selecting the ideal mixer settler depends on several factors - chiefly production capacity, chemical compatibility, and customization options to fit specific process needs. Evaluating supplier reliability, industry reputation, and after-sales support is equally critical. Considerations include availability of different plate thicknesses, material grades like PP, PTFE, or SUS, and optional functionalities such as temperature or pH controls tailored to your operational setting. Scalability and modular installation options facilitate future capacity expansions without major disruptions.
Top Mixer Settler Brands and Manufacturers
Shaanxi Cuiyan Technology Co., Ltd stands out with over a decade of experience delivering advanced mixer settler solutions. With a team of 37+ experts and 100+ patents, the company excels in integrating automation, modularity, and corrosion-resistant materials. Their manufacturing capabilities include precision CNC machining and robotic welding, meeting global standards such as ASME, ISO, and REACH, ensuring equipment compliance even in cross-border projects. Clients benefit from customizable agitator speeds, zero-leak designs, and energy-efficient setups, backed by a comprehensive after-sales service network.

Conclusion
Mixer settlers are indispensable in the chemical industry due to their ability to provide precise, high-efficiency liquid-liquid extraction under diverse conditions. Their modular design, material versatility, and customizable controls meet the rigorous demands of pharmaceuticals, food, cosmetics, and heavy industrial applications. Partnering with an experienced manufacturer like Shaanxi Cuiyan Technology Co., Ltd guarantees access to cutting-edge mixer settlers that deliver robustness, scalability, and compliance with international standards. This makes them a foundational technology for enhancing purity, sustainability, and productivity in modern chemical processing.
FAQs
What is the primary function of a mixer settler?
A mixer settler is utilized for liquid-liquid extraction, enabling separation of components based on their differing solubilities in immiscible liquid phases. This results in efficient purification or recovery of valuable chemicals.
How do I choose the right mixer settler for my process?
Key considerations include required processing volume, chemical compatibility of materials, extraction efficiency, and adaptability to specific separation conditions. Evaluating optional features such as temperature or pH control devices also aligns the equipment with your process needs.
What maintenance is required for mixer settlers?
Maintaining a mixer settler involves periodic inspection of seals and welds, cleaning to prevent fouling, calibration of agitator speeds, and timely replacement of wearing components to ensure continuous optimal performance.
Where to Buy mixer settler?
Shaanxi Cuiyan Technology Co., Ltd offers a comprehensive range of mixer settlers tailored to meet varied industrial needs. With extensive expertise in the design and manufacture of high-purity extraction equipment, Shaanxi Cuiyan stands as a reliable partner in process innovation. Businesses seeking customizable, energy-efficient, and zero-leakage mixer settlers can contact the team to explore solutions aligned with their specific requirements. For inquiries and technical consultation, reach out contact us at wangzhijun@cuiyan-tec.com and discover advanced extraction technology crafted for your success.
References
Seader, J. D., Henley, E. J., & Roper, D. K. (2011). Separation Process Principles. Wiley.
Kuboi, R. (1997). Liquid-liquid Extraction in the Chemical Industry. Elsevier.
Smith, R. (2005). Chemical Process Design and Integration. Wiley.
Rundle, R. E., et al. (2013). Hydrometallurgy of Valuable Metals. Springer.
Fair, J. R. (2007). Industrial Extraction Equipment Handbook. McGraw-Hill.
Liu, X., et al. (2020). Advances in Liquid-Liquid Extraction and Mixer Settler Technologies. Journal of Chemical Engineering Research.











